Autologous blood patch air leak

Methods: Between and , autologous blood patch pleurodesis was used to treat prolonged air leak in 24 patients. Prolonged air leak was due to spontaneous pneumothorax in 17 patients and secondary to pulmonary hydatid cyst operation in 7 patients. The chest tube was unclamped and kept at 60 cm above the patient's chest. After the procedure, the tube was left in its natural position.

The procedure was repeated 24 hours after the first attempt in cases of persistent air leak. Table 1 Chest tube management. Figure 3. Table 3 Propensity-matched analysis of postoperative outcomes. Date of surgery to date of chest tube removal 0. Postoperative outcomes In hospital complications OR 2. Table 4 Propensity-matched analysis of postoperative outcomes using inverse probability weighting. Follow-up data As seen in Figure 2 , of the patients undergoing surgery for a lung nodule or cancer, 66 patients were treated with ABPP.

Figure 4. Limitations and future direction The authors recognize that findings are limited by the retrospective and underpowered nature of this study. Acknowledgments Funding: None.

Notes Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. References 1. Morbidity and mortality of major pulmonary resections in patients with early-stage lung cancer: initial results of the randomized, prospective ACOSOG Z trial. Ann Thorac Surg ; 81 Prolonged air leak following lobectomy can be predicted in lung cancer patients.

Surg Today ; 47 A clinical prediction model for prolonged air leak after pulmonary resection. J Thorac Cardiovasc Surg ; Ann Thorac Surg ; Endobronchial valve treatment for prolonged air leaks of the lung: a case series.

Ann Thorac Surg ; 91 Blood patch for persistent air leak: a review of the current literature. Curr Opin Pulm Med ; 18 PLoS Med ; 4 :e Is blood pleurodesis effective for determining the cessation of persistent air leak?

Interact Cardiovasc Thorac Surg ; 11 The Society of Thoracic Surgeons. Accessed 20th July Robinson CL. Autologous blood for pleurodesis in recurrent and chronic spontaneous pneumothorax.

Canad J Surg ; 30 Chest ; Autologous blood patch pleurodesis in spontaneous pneumothorax with persistent air leak. Scand Cardiovasc J ; 32 Autologous blood pleurodesis: A good choice in patients with persistent air leak. Ann Thorac Med ; 4 Autologous blood patch in persistent air leaks after pulmonary resection. Air leaks after lobectomy increase the risk of empyema but not of cardiopulmonary complications: a case-matched analysis.

Intrapleural instillation of autologous blood in the treatment of prolonged air leak after lobectomy: a prospective randomized controlled trial. Ann Thorac Surg ; 82 Prospective evaluation of biodegradable polymeric sealant for intraoperative air leaks. J Cardiothorac Surg ; 11 Endobronchial valves in the treatment of persistent air leaks. Optimal management of postoperative parenchymal air leaks. J Thorac Dis ; 10 :S Thorac Cardiovasc Surg ; 67 Support Center Support Center.

External link. Please review our privacy policy. Patients discharged with Heimlich valve. Small, 0. Moderate, 2—4 cm. No resolution. Time to resolution of air leak after 1 st ABPP.

Date of surgery to date of chest tube removal. Median days. Q1, Q3 days. In hospital complications OR. Post discharge reoperation HR. Post discharge complication HR. No ABPP. If subjects are randomized to the ABP arm of the trial, they will receive ml of autologous blood sterilely drawn from a peripheral vein and immediately instilled into the chest tube.

Subjects will then follow up either in clinic or via telephone to answer the questionnaire. If the subject is being seen in person, they will be handed a questionnaire form to complete. This form will be kept and stored as source documentation. If the patient is answering the questionnaire via telephone, the study team personnel will record their answers on the questionnaire form, indicating it was completed by the subject but recorded by study team personnel.

A telephone encounter note will be recorded and stored as source with the completed questionnaire. If an air leak is present, ml of autologous blood will be drawn from a peripheral vein and immediately instilled into the chest tube. The individual who draws blood is that the discretion of the site principal investigator. The tubing will be elevated over an IV pole while the patient remains in bed, moving position every 15 minutes for 1 hour to distribute the blood throughout the pleural cavity.

The tubing support will then be removed, allowing the chest tube to drain. After ABP intervention, the chest tube will remain to water seal, as long as the patient tolerates it. This may mean postoperative observation, of another type of intervention. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below.

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